The storyline was based off the novel Mutsu by Yo Kusakabe. Eisuke Tameyori (Hidetoshi Nishijima) is a middle-aged private practice physician (general practitioner.) He has the ability to diagnose someone's condition just by looking at them. He is also able to recognize people who will commit crimes in the future by looking for certain symptoms, which he calls 'The markers of Criminal Intent'. Aftermeeting Detective Junichiro Hayase (Atsushi Ito), they soon work together to solve cases.